Unchained Labs

Unchained Labs designs and sells laboratory instruments from a Pleasanton campus at 4747 Willow Road, in the office and research district on the north side of the city near Interstate 580. Older directory records, including the one this listing started from, place the company at 6870 Koll Center Parkway. That was its address before September 2023, when, according to the company, it moved into a 121,000 square foot building on Willow Road that brought three earlier California sites under one roof. The main number, 925-587-9800, carried over to the new address.

Instruments for biologics and gene therapy labs

The company's own site groups its products into three families. For biologics developers it sells analytical instruments with memorable names: Aunty for protein stability, Stunner for quantification and sizing by dynamic light scattering and UV/Vis, Honeybun for viscosity, Lunatic for UV/Vis quantification and Lil' Tuna for buffer exchange. For gene therapy and nanoparticle work there is Leprechaun, aimed at lentivirus and exosome characterization, the Sunscreen, Sunshine and Sunbather systems for nanoparticle synthesis, and Stunner AF for sizing and encapsulation of lipid nanoparticles. A third line is lab automation the company calls AI-native, including the AI Developability Workcell and a system named Stuntman.

The buyers are researchers rather than households: teams working on antibodies and other biologics, AAV and lentiviral gene therapies, lipid nanoparticles, cell therapy and exosomes. Beyond Pleasanton the company lists offices in Brighton, Massachusetts; Gent, Belgium; Royston, England; Shanghai; and Tokyo.

Approaching an instrument vendor

A lab weighing equipment like this usually starts with its own samples. Ask whether the company can run a demonstration or a test on your material, how much sample each instrument consumes, and what the software exports to your data systems. Get installation, training and service terms in writing before purchase, including how quickly a field engineer can reach a Bay Area lab. Groups working under GMP should ask what documentation comes with the software for validation. The import record names Roman Benitez as a manager; that contact has not been checked, so the main line is the safer first call.

Pleasanton and the Tri-Valley

The campus sits in the Tri-Valley corner of Alameda County, a short drive from Dublin, Livermore and Sunol, and within reach of labs in Castro Valley, Hayward, Union City and Fremont. Visitors can use the Dublin/Pleasanton BART station or the Interstate 580 and 680 interchange nearby.

Call 925-587-9800 and confirm the Willow Road address before visiting or shipping samples, since some online directories still show the old Koll Center location. Product pages and regional contacts are on unchainedlabs.com.